Used Leistritz ZSE 27 HP-PH-40D Twin Screw Extruder System – Complete Pharma Line with Chiller & Granulator (2010)

Manufacturer: Leistritz
Model: ZSE 27 HP-PH-40D
Machine Type: Co-Rotating Twin Screw Extruder System
Screw Diameter: 27 mm
L/D Ratio: 40:1
Capacity: Approx. 200 kg/hr (440 lbs/hr)
Screw Speed: Up to 500 RPM
Construction: Hastelloy C-276
Drive: 22.5 HP (15 kW), 1750 RPM AC Motor
Electrical: 400V
Year Built: 2010
Condition: Used
Previous Application: Pharmaceutical Processing

Description

Used Leistritz ZSE 27 HP-PH-40D twin screw extruder system, configured as a complete pharmaceutical-grade extrusion line. This unit features co-rotating 27 mm twin screws with a 40:1 L/D ratio, delivering high-performance mixing, compounding, and hot melt extrusion capabilities.

The system includes 10 barrel sections with (9) heated zones, utilizing electrical heating and water cooling for precise thermal control. The Hastelloy C-276 construction ensures excellent corrosion resistance and suitability for high-purity and aggressive formulations.

Driven by a 22.5 HP (15 kW), 1750 RPM AC motor via gearbox, the extruder supports screw speeds up to 500 RPM, offering flexibility for various processing conditions.

This package includes a full downstream and support system:

• K-Tron feeding unit for accurate material dosing

• (3) temperature control units

• SKA-12-W chiller for process cooling

• Granulator for pelletizing output material

• Electrical control cabinet

• Spare parts package

Previously used in a pharmaceutical application, this system is ideal for regulated environments requiring precision, repeatability, and high cleanliness standards.

Specifications

• Manufacturer: Leistritz

• Model: ZSE 27 HP-PH-40D

• Machine Type: Twin screw extruder (co-rotating)

• Screw Diameter: 27 mm

• Configuration: Twin, side-by-side screws

• L/D Ratio: 40:1

• Capacity: Approx. 200 kg/hr (440 lbs/hr)

• Maximum Screw Speed: 500 RPM

• Barrel Sections: 10

• Heated Barrels: 9

• Heating/Cooling: Electrically heated, water cooled

• Material of Construction: Hastelloy C-276

• Drive Motor: 22.5 HP / 15 kW AC motor

• Motor Speed: 1750 RPM

• Electrical: 400V

• Weight: Approx. 1.2 tonnes

• Dimensions: 3650 mm L x 1150 mm W x 1800 mm H

• Included Equipment:

  • K-Tron feeder unit

  • (3) temperature control units

  • SKA-12-W chiller

  • Granulator

  • Electrical cabinet

  • Spare parts

• Serial Number: 3899

• Year Built: 2010

• Previous Use: Pharmaceutical processing

• Condition: Used

Applications

This extrusion system is commonly used for:

• Pharmaceutical hot melt extrusion (HME)

• Polymer compounding

• Nutraceutical processing

• Specialty chemical production

• Masterbatch manufacturing

• Food extrusion

• R&D and pilot scale production

• Additive dispersion

• Controlled release formulation production

• High-purity material processing

What Might This Be Used For

• Producing pharmaceutical dosage forms

• Polymer blending and compounding

• Creating controlled-release drug formulations

• Mixing additives into plastics

• Producing pellets via granulation

• Processing nutraceutical ingredients

• Developing specialty chemical formulations

• Running pilot-scale production

• Conducting extrusion trials

• Manufacturing high-performance materials

Materials This Machine Can Process

• Pharmaceutical APIs and excipients

• Polymers and resins

• Plastics and additives

• Nutraceutical compounds

• Specialty chemicals

• Masterbatch materials

• Bio-based materials

• High-purity compounds

• Food-grade materials

• Experimental formulations

Manufacturer Information

Leistritz is a leading manufacturer of twin screw extrusion systems, widely used in pharmaceutical, polymer, and specialty industries. The ZSE series is known for its modular design, precision control, and high-performance mixing, making it ideal for both production and research environments.